Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18005401 | 0.80 | TSHR (0.51) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL18005321 | 0.78 | TSHR (0.55) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13033934 | 0.75 | KMT2A (0.56) | KDM4EKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL18005647 | 0.74 | ALDH1A1 (0.44) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL15080590 | 0.73 | TSHR (0.57) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL18005310 | 0.72 | HSD17B10 (0.44) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL1708189 | 0.71 | KMT2A (0.56) | KDM4EKMT2AMEN1ALDH1A1ATM | |
| SCHEMBL19122795 | 0.71 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL18063512 | 0.71 | CASP1 (0.44) | KDM4EKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL13693076 | 0.69 | KMT2A (0.55) | KDM4EKMT2AMEN1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016133959-A9 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-02-22 | — | — | WO | disclosed |