Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 14/20 | 0.50 |
| ▸ | CA1 | P00915 | 12/20 | 0.50 |
| ▸ | CA2 | P00918 | 12/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16231516 | 0.90 | USP2 (0.64) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL24594128 | 0.84 | USP2 (0.64) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL18211419 | 0.83 | USP2 (0.61) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL12637647 | 0.83 | USP2 (0.72) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL12045940 | 0.83 | USP2 (0.68) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL13880697 | 0.82 | USP2 (0.62) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL14642481 | 0.82 | USP2 (0.62) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| 6-Carboxyfluorescein SCHEMBL9906208 | 0.81 | USP2 (0.69) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| 6-Carboxyfluorescein SCHEMBL29369299 | 0.81 | USP2 (0.69) | USP2L3MBTL1DNASE1L3PRMT1MEN1 | |
| SCHEMBL12061907 | 0.81 | USP2 (0.66) | USP2L3MBTL1DNASE1L3PRMT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180051314-A1 | COMPOUNDS, SUBSTRATES AND METHODS RELATED TO HISTONE DEACETYLASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180051314-A1 | COMPOUNDS, SUBSTRATES AND METHODS RELATED TO HISTONE DEACETYLASES | HDAC1, HDAC11, HDAC10 | USP2 1251/4885L3MBTL1 728/4885DNASE1L3 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.