Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | PLEC | Q15149 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 15/20 | 0.56 |
| ▸ | CA1 | P00915 | 13/20 | 0.56 |
| ▸ | CA2 | P00918 | 13/20 | 0.56 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16231516 | 0.93 | USP2 (0.64) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL12637546 | 0.89 | USP2 (0.57) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL23225857 | 0.88 | USP2 (0.67) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL23625147 | 0.86 | USP2 (0.55) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL10098714 | 0.86 | USP2 (0.76) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL21945707 | 0.86 | USP2 (0.59) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL19543669 | 0.85 | USP2 (0.69) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL10060092 | 0.85 | USP2 (0.72) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL18383481 | 0.85 | USP2 (0.68) | USP2L3MBTL1MEN1POLBKMT2A | |
| SCHEMBL16541409 | 0.85 | USP2 (0.68) | USP2L3MBTL1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023242662-A2 | POLYMERIC TANDEM DYES WITH SPACING LINKER GROUPS | Sony Group Corporation (JP) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023006909-A1 | FUNCTIONALISATION OF CARBOXYMETHYLCELLULOSE | THE UNIVERSITY OF MANCHESTER (GB) | 2023-02-02 | — | — | WO | disclosed |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2021-03-02 | — | — | US | disclosed |
| US-10626438-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | THE BROAD INSTITUTE, INC. (US) | 2020-04-21 | — | — | US | disclosed |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2020-02-04 | — | — | US | disclosed |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2019-05-16 | — | — | US | disclosed |
| US-10174094-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC (GB) | 2019-01-08 | — | — | US | disclosed |
| US-20180155760-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | BROAD INST INC (US) | 2018-06-07 | — | — | US | disclosed |
| US-20180155760-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | BROAD INST INC (US) | 2018-06-07 | — | — | US | disclosed |
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2018-04-19 | — | — | US | disclosed |
| US-20180051314-A1 | COMPOUNDS, SUBSTRATES AND METHODS RELATED TO HISTONE DEACETYLASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-22 | — | — | US | disclosed |
| US-20180051314-A1 | COMPOUNDS, SUBSTRATES AND METHODS RELATED TO HISTONE DEACETYLASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-22 | — | — | US | disclosed |
| US-9856509-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | THE BROAD INSTITUTE, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| US-9745613-B2 | Compounds, substrates and methods related to histone deacetylases | THE BROAD INSTITUTE, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-9745613-B2 | Compounds, substrates and methods related to histone deacetylases | THE BROAD INSTITUTE, INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160060679-A1 | COMPOUNDS, SUBSTRATES AND METHODS RELATED TO HISTONE DEACETYLASES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-03 | — | — | US | disclosed |
| US-20140335550-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | THE BROAD INSTITUTE, INC. (US) | 2014-11-13 | — | — | US | disclosed |
| US-20110105496-A1 | Methods For The Treatment Of Myosin Heavy Chain-Mediated Conditions Using 4,7-Dihydrothieno[2,3-B]Pyridine Compounds | GILEAD COLORADO, INC. | 2011-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174094-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | USP2 2243/4885L3MBTL1 3395/4885MEN1 1641/4885 |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | USP2 2243/4885L3MBTL1 3395/4885MEN1 1641/4885 |
| US-20180051314-A1 | COMPOUNDS, SUBSTRATES AND METHODS RELATED TO HISTONE DEACETYLASES | HDAC1, HDAC11, HDAC10 | USP2 1251/4885L3MBTL1 728/4885MEN1 1202/4885 |
| US-20180104354-A1 | CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF | ICOS, HAVCR2, CD2 | USP2 1198/4885L3MBTL1 1952/4885MEN1 4384/4885 |
| US-20180155760-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | KDM1A, MAN2B1, KDM3A | USP2 619/4885L3MBTL1 242/4885MEN1 536/4885 |
| US-10626438-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | KDM1A, MAN2B1, KDM3A | USP2 619/4885L3MBTL1 242/4885MEN1 536/4885 |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | USP2 2243/4885L3MBTL1 3395/4885MEN1 1641/4885 |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | USP2 2243/4885L3MBTL1 3395/4885MEN1 1641/4885 |
| US-20110105496-A1 | Methods For The Treatment Of Myosin Heavy Chain-Mediated Conditions Using 4,7-Dihydrothieno[2,3-B]Pyridine Compounds | MYH2, MYLK2, TNNI3 | USP2 2470/4885L3MBTL1 2800/4885MEN1 3190/4885 |
| US-20140335550-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | MAN2B1, KDM1A, KDM3A | USP2 615/4885L3MBTL1 301/4885MEN1 666/4885 |
| US-20160060679-A1 | COMPOUNDS, SUBSTRATES AND METHODS RELATED TO HISTONE DEACETYLASES | HDAC1, HDAC11, HDAC10 | USP2 1344/4885L3MBTL1 765/4885MEN1 1124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.