Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | XDH | P47989 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA7 | P43166 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.57 |
| ▸ | ERN1 | O75460 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14699819 | 0.92 | LMNA (0.77) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL399645 | 0.88 | KDM4E (0.60) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL31395255 | 0.88 | KDM4E (0.60) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL752914 | 0.87 | KDM4E (0.58) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL1312438 | 0.87 | KDM4E (0.58) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL29742519 | 0.87 | POLB (0.58) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL197521 | 0.87 | POLB (0.58) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL400542 | 0.87 | POLB (0.58) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL17894021 | 0.87 | LMNA (0.58) | KDM4ETDP1POLBXDHL3MBTL1 | |
| SCHEMBL30152820 | 0.87 | KDM4E (0.58) | KDM4ETDP1POLBXDHL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300965-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-09-12 | — | — | US | disclosed |
| US-11999746-B2 | Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2024-06-04 | — | — | US | disclosed |
| US-20220157484-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-05-19 | — | — | US | disclosed |
| US-20200055863-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-02-20 | — | — | US | disclosed |
| US-20200055863-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-02-20 | — | — | US | disclosed |
| US-10428078-B2 | Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-10-01 | — | — | US | disclosed |
| US-10428078-B2 | Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-10-01 | — | — | US | disclosed |
| EP-3172211-B1 | TRICYCLIC IMIDAZO-PYRIMIDINONE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY LP-PLA2 | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-07-03 | — | — | EP | disclosed |
| EP-3172211-B1 | TRICYCLIC IMIDAZO-PYRIMIDINONE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY LP-PLA2 | GLAXOSMITHKLINE IP DEV LTD (GB) | 2019-07-03 | — | — | EP | disclosed |
| US-20190023715-A1 | COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-24 | — | — | US | disclosed |
| US-20080319080-A1 | Amide Compounds and Their Use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1940780-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1940779-A2 | AMIDE COMPOUNDS AND THEIR USE | Sumitomo Chemical Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20080058544-A1 | Liquid crystalline organic semiconductor material and organic semiconductor device using same | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-03-06 | — | — | US | disclosed |
| WO-2007049729-A2 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007049728-A1 | AMIDE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | WO | disclosed |
| EP-0734363-B1 | FLUORINATION PROCESS | F2 CHEMICALS LIMITED (GB) | 1999-07-21 | — | — | EP | disclosed |
| US-5900502-A | Fluorination process | BNFL FLUOROCHEMICALS LIMITED (GB) | 1999-05-04 | — | — | US | disclosed |
| EP-0734363-A1 | FLUORINATION PROCESS | BNFL FLUOROCHEMICALS LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016649-A1 | FLUORINATION PROCESS | BNFL FLUOROCHEMICALS LTD. (GB) | 1995-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200055863-A1 | COMPOUNDS | PLAAT2, PLA2G12A, PLA2G1B | KDM4E 3774/4885TDP1 1614/4885POLB 3233/4885 |
| US-20190023715-A1 | COMPOUNDS | PLAAT2, PLA2G12A, PLA2G1B | KDM4E 3774/4885TDP1 1614/4885POLB 3233/4885 |
| US-20080058544-A1 | Liquid crystalline organic semiconductor material and organic semiconductor device using same | SLCO4C1, SLCO2A1, SLCO1A2 | KDM4E 1636/4885TDP1 3079/4885POLB 1422/4885 |
| US-10428078-B2 | Compounds | PLAAT2, PLA2G12A, PLA2G1B | KDM4E 3774/4885TDP1 1614/4885POLB 3233/4885 |
| US-20240300965-A1 | COMPOUNDS | PLAAT2, PLA2G12A, PLA2G1B | KDM4E 3774/4885TDP1 1614/4885POLB 3233/4885 |
| US-11999746-B2 | Compounds | PLAAT2, PLA2G12A, PLA2G1B | KDM4E 3774/4885TDP1 1614/4885POLB 3233/4885 |
| US-20080319080-A1 | Amide Compounds and Their Use | NAT1, ACAT2, NAAA | KDM4E 1715/4885TDP1 2896/4885POLB 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.