SCHEMBL19896296

SCHEMBL19896296

CCCCn1c2cc(N=C(c3ccccc3)c3ccccc3)ccc2c2ccc(N=C(c3ccccc3)c3ccccc3)cc21

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 8/20 0.46
▸ PSEN1 P49768 6/20 0.43
▸ PSEN2 P49810 6/20 0.43
▸ APH1B Q8WW43 6/20 0.43
▸ NCSTN Q92542 6/20 0.43
▸ APH1A Q96BI3 6/20 0.43
▸ PSENEN Q9NZ42 6/20 0.43
▸ ALPL P05186 1/20 0.42
▸ ALPG P10696 1/20 0.42
▸ ALDH1A1 P00352 3/20 0.40
▸ PGR P06401 1/20 0.40
▸ RORA P35398 1/20 0.40
▸ RORC P51449 1/20 0.40
▸ RORB Q92753 1/20 0.40
▸ CNR1 P21554 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.39
▸ HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19896356 0.95 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896353 0.95 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896452 0.95 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896470 0.93 CNR2 (0.41) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896396 0.93 CNR2 (0.41) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896358 0.85 LPL (0.38) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896333 0.84 CNR2 (0.46) CNR2ALDH1A1CNR1KDM4EHPGD
SCHEMBL19896260 0.82 HDAC6 (0.42) KDM4E
SCHEMBL19896431 0.82 HTR7 (0.45) CNR2
SCHEMBL19896383 0.81 MAPT (0.45) ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 CNR2 1308/4885PSEN1 4699/4885PSEN2 4790/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 CNR2 1308/4885PSEN1 4699/4885PSEN2 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback