SCHEMBL19896358

SCHEMBL19896358

CCCCn1c2cc(N=C(c3ccccc3)c3ccccc3)ccc2c2ccc(B3OC(C)(C)C(C)(C)O3)cc21

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ LPL P06858 7/20 0.38
▸ LIPG Q9Y5X9 7/20 0.38
▸ CNR2 P34972 5/20 0.36
▸ PSEN1 P49768 5/20 0.34
▸ PSEN2 P49810 5/20 0.34
▸ APH1B Q8WW43 5/20 0.34
▸ NCSTN Q92542 5/20 0.34
▸ APH1A Q96BI3 5/20 0.34
▸ PSENEN Q9NZ42 5/20 0.34
▸ P4HB P07237 1/20 0.34
▸ ALPL P05186 1/20 0.33
▸ ALPG P10696 1/20 0.33
▸ F2 P00734 1/20 0.33
▸ F11 P03951 1/20 0.33
▸ PRSS1 P07477 1/20 0.33
▸ PRSS2 P07478 1/20 0.33
▸ PRSS3 P35030 1/20 0.33
▸ CNR1 P21554 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19896296 0.85 CNR2 (0.46) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896452 0.81 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896353 0.81 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896356 0.81 CNR2 (0.50) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL15106752 0.81 LPL (0.47) LPLLIPGCNR2PSEN1PSEN2
SCHEMBL19896470 0.79 CNR2 (0.41) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL19896396 0.79 CNR2 (0.41) CNR2PSEN1PSEN2APH1BNCSTN
SCHEMBL17445277 0.78 LPL (0.52) LPLLIPGPSEN1PSEN2APH1B
SCHEMBL21370573 0.78 LPL (0.52) LPLLIPGPSEN1PSEN2APH1B
SCHEMBL6364825 0.78 LPL (0.52) LPLLIPGPSEN1PSEN2APH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-10421779-B2 Carbazole compound having anti-virus activity KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2019-09-24 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2018-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057527-A1 CARBAZOLE COMPOUND HAVING ANTI-VIRUS ACTIVITY ZC3HAV1, ZC3HAV1L, GTF3C3 LPL 2495/4885LIPG 2311/4885CNR2 1308/4885
US-10421779-B2 Carbazole compound having anti-virus activity ZC3HAV1, ZC3HAV1L, GTF3C3 LPL 2495/4885LIPG 2311/4885CNR2 1308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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