Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL303519 | 0.88 | HTR2C (0.45) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL3260086 | 0.86 | TSHR (0.39) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL309786 | 0.85 | CNR2 (0.38) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL1976194 | 0.83 | CNR2 (0.39) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL3261430 | 0.82 | HTR2C (0.40) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL303078 | 0.78 | CNR2 (0.55) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL1966538 | 0.77 | LMNA (0.42) | HTR6MEN1KMT2ALMNABACE1 | |
| SCHEMBL315878 | 0.76 | NTRK1 (0.33) | CNR2ALDH1A1LMNABACE1L3MBTL1 | |
| SCHEMBL3275051 | 0.75 | HTR2C (0.45) | HTR2CHTR1AHTR2AHTR7DRD3 | |
| SCHEMBL3260082 | 0.74 | LMNA (0.50) | MEN1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334637-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | disclosed |