Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976194 | 0.91 | CNR2 (0.39) | TSHRLMNAHPGDNPC1RAB9A | |
| SCHEMBL3260082 | 0.89 | LMNA (0.50) | TSHRLMNAHPGDNPC1RAB9A | |
| SCHEMBL3261430 | 0.86 | HTR2C (0.40) | TSHRLMNAHPGDCNR2SMN1; SMN2 | |
| SCHEMBL1989680 | 0.86 | HTR2C (0.37) | LMNANPC1CNR2MAPTSMN1; SMN2 | |
| SCHEMBL3275051 | 0.85 | HTR2C (0.45) | TSHRHPGDNPC1RAB9ACNR2 | |
| SCHEMBL315878 | 0.81 | NTRK1 (0.33) | TSHRLMNAHPGDNPC1RAB9A | |
| SCHEMBL3261428 | 0.76 | MAPK1 (0.41) | LMNACNR2SMN1; SMN2ALDH1A1HTR1A | |
| SCHEMBL304191 | 0.74 | LMNA (0.37) | LMNAHPGDRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3230248 | 0.74 | LMNA (0.57) | TSHRLMNAHPGDNPC1RAB9A | |
| SCHEMBL1966848 | 0.73 | HTR2C (0.49) | LMNACNR2SMN1; SMN2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | disclosed |