Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 3/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | USP14 | P54578 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1989753 | 1.00 | L3MBTL1 (0.44) | L3MBTL1SMN1; SMN2JAK1JAK2RECQL | |
| SCHEMBL2002226 | 0.83 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2RECQLKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1990766 | 0.80 | RECQL (0.51) | L3MBTL1SMN1; SMN2RECQLALDH1A1PTGDR2 | |
| Hydrochloric Acid SCHEMBL1990769 | 0.80 | RECQL (0.51) | L3MBTL1SMN1; SMN2RECQLALDH1A1PTGDR2 | |
| SCHEMBL1992150 | 0.79 | SMN1; SMN2 (0.48) | L3MBTL1SMN1; SMN2RECQLALDH1A1PTGDR2 | |
| SCHEMBL1992151 | 0.79 | SMN1; SMN2 (0.48) | L3MBTL1SMN1; SMN2RECQLALDH1A1PTGDR2 | |
| SCHEMBL1992571 | 0.77 | SMN1; SMN2 (0.48) | L3MBTL1SMN1; SMN2RECQLALDH1A1PTGDR2 | |
| SCHEMBL28542915 | 0.71 | JAK1 (0.47) | L3MBTL1JAK1JAK2KMT2ADRD2 | |
| SCHEMBL28542917 | 0.71 | JAK1 (0.47) | L3MBTL1JAK1JAK2KMT2ADRD2 | |
| SCHEMBL1990506 | 0.71 | CHRM2 (0.47) | SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | L3MBTL1 3898/4885SMN1; SMN2 2548/4885JAK1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.