Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2002226 | 0.87 | L3MBTL1 (0.50) | SMN1; SMN2RECQLALDH1A1L3MBTL1LMNA | |
| SCHEMBL1996095 | 0.84 | PTGDR2 (0.42) | ALDH1A1PTGDR2 | |
| Hydrochloric Acid SCHEMBL1990769 | 0.84 | RECQL (0.51) | SMN1; SMN2RECQLALDH1A1PTGDR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1990766 | 0.84 | RECQL (0.51) | SMN1; SMN2RECQLALDH1A1PTGDR2L3MBTL1 | |
| SCHEMBL1992150 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2RECQLALDH1A1PTGDR2L3MBTL1 | |
| SCHEMBL1992151 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2RECQLALDH1A1PTGDR2L3MBTL1 | |
| SCHEMBL2856965 | 0.78 | L3MBTL1 (0.54) | SMN1; SMN2ALDH1A1L3MBTL1HTTKDM4E | |
| SCHEMBL1989753 | 0.77 | L3MBTL1 (0.44) | SMN1; SMN2RECQLALDH1A1PTGDR2L3MBTL1 | |
| SCHEMBL1989752 | 0.77 | L3MBTL1 (0.44) | SMN1; SMN2RECQLALDH1A1PTGDR2L3MBTL1 | |
| SCHEMBL5323230 | 0.74 | SMN1; SMN2 (0.73) | SMN1; SMN2RECQLALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079105-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | SMN1; SMN2 2548/4885RECQL 3604/4885ALDH1A1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.