Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 10/20 | 0.40 |
| ▸ | LPL | P06858 | 9/20 | 0.40 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15000455 | 0.87 | LIPG (0.40) | LIPGLPLF11UCHL1ESR2 | |
| SCHEMBL13531863 | 0.84 | LIPG (0.43) | LIPGLPLF11UCHL1ESR2 | |
| SCHEMBL18353771 | 0.82 | LIPG (0.53) | LIPGLPLF11UCHL1ESR2 | |
| SCHEMBL30577723 | 0.82 | F11 (0.41) | LIPGLPLF11UCHL1ESR2 | |
| SCHEMBL2699203 | 0.82 | LIPG (0.39) | LIPGLPLF11UCHL1ESR2 | |
| SCHEMBL14707184 | 0.82 | LIPG (0.39) | LIPGLPLF11UCHL1ESR2 | |
| SCHEMBL5265730 | 0.81 | GAA (0.40) | LIPGLPLUCHL1HSD17B10 | |
| SCHEMBL22589556 | 0.81 | LPL (0.38) | LIPGLPLF11UCHL1ESR2 | |
| SCHEMBL19675305 | 0.81 | LIPG (0.38) | LIPGLPLF11UCHL1ESR2 | |
| SCHEMBL29421509 | 0.81 | LPL (0.38) | LIPGLPLF11UCHL1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2018037120-A1 | PRODRUGS ACTIVATED BY REACTIVE OXYGEN SPECIES FOR USE IN THE TREATMENT OF INFLAMMATORY DISEASES AND CANCER | DANMARKS TEKNISKE UNIVERSITET (DK) | 2018-03-01 | — | — | WO | disclosed |
| WO-2018037120-A1 | PRODRUGS ACTIVATED BY REACTIVE OXYGEN SPECIES FOR USE IN THE TREATMENT OF INFLAMMATORY DISEASES AND CANCER | DANMARKS TEKNISKE UNIVERSITET (DK) | 2018-03-01 | — | — | WO | disclosed |