Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900143 | 0.77 | ALDH1A1 (0.51) | ALDH1A1GBA1CYP1A2MEN1KMT2A | |
| SCHEMBL19900144 | 0.71 | ALDH1A1 (0.36) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL19900199 | 0.71 | CHRM3 (0.36) | ALDH1A1CYP1A2CHRM3PDE4APDE4B | |
| SCHEMBL15055333 | 0.71 | CHRM3 (0.46) | ALDH1A1SMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL15246924 | 0.70 | ALDH1A1 (0.52) | ALDH1A1GBA1POLBSMN1; SMN2CYP1A2 | |
| SCHEMBL19899801 | 0.70 | NPY5R (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL19900131 | 0.70 | NPY5R (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL18005531 | 0.70 | KDM4E (0.35) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL18280292 | 0.69 | CHRM3 (0.49) | ALDH1A1SMN1; SMN2CYP1A2CHRM3PDE4A | |
| SCHEMBL9803306 | 0.68 | HRH1 (0.62) | ALDH1A1SMN1; SMN2CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595250-B2 | Substituted pyrimidine compounds as multifunctional radical quenchers and their uses | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2026-04-07 | — | — | US | disclosed |
| US-20220324841-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-10-13 | — | — | US | disclosed |
| US-11390605-B2 | Substituted pyrimidine compounds as multifunctional radical quenchers and their uses | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-07-19 | — | — | US | disclosed |
| US-20210276979-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-09-09 | — | — | US | disclosed |
| US-20210276979-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2021-09-09 | — | — | US | disclosed |
| WO-2018039077-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-01 | — | — | WO | disclosed |
| WO-2018039077-A1 | THERAPEUTIC COMPOUNDS | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595250-B2 | Substituted pyrimidine compounds as multifunctional radical quenchers and their uses | GSR, UQCRC1, TXNRD2 | ALDH1A1 573/4885GBA1 777/4885POLB 695/4885 |
| US-20220324841-A1 | THERAPEUTIC COMPOUNDS | CFTR, F12, FURIN | ALDH1A1 674/4885GBA1 31/4885POLB 4601/4885 |
| US-20210276979-A1 | THERAPEUTIC COMPOUNDS | CFTR, F12, FURIN | ALDH1A1 674/4885GBA1 31/4885POLB 4601/4885 |
| US-11390605-B2 | Substituted pyrimidine compounds as multifunctional radical quenchers and their uses | DPYD, TYMP, NUDT1 | ALDH1A1 599/4885GBA1 2092/4885POLB 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.