SCHEMBL1990109

SCHEMBL1990109

Cc1nc(NC(=O)OC(C)(C)C)sc1C(=O)N[C@@H](C)C1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LCK P06239 6/20 0.53
LMNA P02545 1/20 0.49
PI4KB Q9UBF8 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL772092 0.81 LCK (0.61) LCKPI4KBMEN1KMT2ANPC1
SCHEMBL771999 0.80 LCK (0.54) LCKLMNAPI4KBNPC1RAB9A
SCHEMBL19778766 0.79 LCK (0.58) LCKPI4KBNPC1CYP2C9
SCHEMBL1987487 0.79 LCK (0.39) LCKSMN1; SMN2
SCHEMBL775229 0.78 LCK (0.59) LCKLMNAMEN1KMT2AL3MBTL1
SCHEMBL12599534 0.76 ALDH1A1 (0.52) LCKLMNAKMT2ANPC1RAB9A
SCHEMBL773470 0.75 LCK (0.66) LCKPI4KBMEN1KMT2ANPC1
SCHEMBL1983158 0.75 LCK (0.39) LCK
SCHEMBL772999 0.74 LCK (0.53) LCKPI4KBNPC1
SCHEMBL1987380 0.74 ALDH1A1 (0.54) LCKLMNAKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2222655-B1 N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL SUMITOMO CHEMICAL CO (JP) 2011-06-29 EP disclosed
EP-2222655-B1 N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL SUMITOMO CHEMICAL CO (JP) 2011-06-29 EP disclosed
US-20100298391-A1 AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-25 US disclosed
US-20100298391-A1 AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-25 US disclosed
US-20100298391-A1 AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-25 US disclosed
WO-2009066790-A1 N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100298391-A1 AMIDE COMPOUNDS AND USE THEREOF FOR PLANT DISEASE CONTROL CYC1, NAT1, CYCS LCK 2767/4885LMNA 4282/4885PI4KB 2644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.