Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29023892 | 0.83 | KDM4E (0.65) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15353018 | 0.82 | KMT2A (0.65) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3925744 | 0.82 | LMNA (0.78) | LMNAKMT2ASMN1; SMN2CA12CA2 | |
| SCHEMBL6302286 | 0.82 | LMNA (0.55) | LMNAMEN1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL2178212 | 0.78 | KMT2A (0.65) | LMNAMEN1KMT2ACA12CA2 | |
| SCHEMBL2407197 | 0.76 | L3MBTL1 (0.66) | LMNAMEN1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL2177411 | 0.75 | NPC1 (0.56) | LMNAMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL28007728 | 0.73 | KDM4E (0.68) | LMNAMEN1KMT2ASMN1; SMN2CA12 | |
| SCHEMBL2179378 | 0.73 | ALDH1A1 (0.61) | LMNAMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL2177227 | 0.73 | KMT2A (0.55) | LMNAMEN1KMT2ASMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902713-B2 | Neuroprotective compounds and use thereof | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-02-27 | — | — | US | disclosed |