Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24617111 | 0.76 | KIF11 (0.49) | ARKIF11ASIC1 | |
| SCHEMBL24617126 | 0.76 | AR (0.39) | ARALDH1A1MAPTKIF11CTSS | |
| SCHEMBL19901483 | 0.76 | GABRA1 (0.35) | ARCYP11B1CYP11B2GABRA1GABRG2 | |
| SCHEMBL15853137 | 0.75 | ALDH1A1 (0.46) | ARALDH1A1MAPTKIF11GABRG2 | |
| SCHEMBL19901491 | 0.75 | FNTA (0.38) | ALDH1A1CYP11B1CYP11B2GABRA1GABRG2 | |
| SCHEMBL24617025 | 0.72 | HTT (0.45) | ARALDH1A1MAPTKIF11CTSS | |
| SCHEMBL15853136 | 0.72 | FNTA (0.50) | ALDH1A1KIF11 | |
| SCHEMBL8569423 | 0.71 | CLK1 (0.37) | ARALDH1A1MAPTGABRA1 | |
| SCHEMBL24617024 | 0.70 | SLC22A12 (0.39) | ARALDH1A1KIF11CTSSCTSK | |
| SCHEMBL23621508 | 0.70 | KIF11 (0.47) | ARALDH1A1PGRKIF11CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9905776-B2 | Pyrene-based compound and organic light-emitting diode comprising the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-02-27 | — | — | US | disclosed |