Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406654 | 0.81 | MEN1 (0.59) | MEN1ALDH1A1KMT2ATAAR1CHRM5 | |
| SCHEMBL28221267 | 0.81 | ALDH1A1 (0.56) | MEN1ALDH1A1KMT2ACHRM5MAPT | |
| SCHEMBL6906151 | 0.81 | ALDH1A1 (0.56) | MEN1ALDH1A1KMT2ACHRM5MAPT | |
| SCHEMBL22791460 | 0.81 | TAAR1 (0.57) | MEN1ALDH1A1KMT2ATAAR1CHRM5 | |
| SCHEMBL29042852 | 0.79 | CHRM5 (0.56) | MEN1ALDH1A1KMT2ATAAR1CHRM5 | |
| SCHEMBL1029483 | 0.77 | PARP1 (0.58) | MEN1ALDH1A1KMT2ATAAR1CHRM5 | |
| SCHEMBL14198012 | 0.77 | CHRM5 (0.58) | MEN1ALDH1A1KMT2ATAAR1CHRM5 | |
| SCHEMBL9416087 | 0.77 | TAAR1 (0.53) | MEN1ALDH1A1KMT2ATAAR1CHRM5 | |
| SCHEMBL28577973 | 0.76 | KMT2A (0.65) | MEN1ALDH1A1KMT2ACHRM5MAPT | |
| SCHEMBL7684603 | 0.76 | NPC1 (0.65) | ALDH1A1CHRM5CYP19A1NQO2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9901567-B2 | Substituted CC-1065 analogs and their conjugates | SYNTARGA B.V. (NL) | 2018-02-27 | — | — | US | disclosed |