Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.33 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081997 | 1.00 | MEN1 (0.35) | MEN1KMT2AMITFPOLBRAB9A | |
| SCHEMBL620199 | 0.94 | GUCY1B2 (0.34) | MEN1KMT2APDE3BTAS1R3TAS1R1 | |
| SCHEMBL620198 | 0.94 | GUCY1B2 (0.34) | MEN1KMT2APDE3BTAS1R3TAS1R1 | |
| SCHEMBL620495 | 0.89 | ALDH1A1 (0.37) | MEN1KMT2APOLBRAB9AKDM4E | |
| SCHEMBL620496 | 0.89 | ALDH1A1 (0.37) | MEN1KMT2APOLBRAB9AKDM4E | |
| SCHEMBL18080681 | 0.85 | MEN1 (0.40) | MEN1KMT2AMITFPOLBRAB9A | |
| SCHEMBL28455506 | 0.85 | GABRP (0.37) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL28455508 | 0.85 | GABRP (0.37) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL620660 | 0.83 | MEN1 (0.36) | MEN1KMT2APOLBRAB9AKDM4E | |
| SCHEMBL620519 | 0.82 | TAS1R3 (0.35) | MEN1KMT2ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |