Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24680076 | 0.87 | KDM4E (0.53) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL5502679 | 0.81 | KDM4E (0.55) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL16395688 | 0.77 | POLB (0.51) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL3490308 | 0.76 | AKR1C3 (0.56) | KDM4EGLAMYCNR4A1POLB | |
| SCHEMBL3172075 | 0.76 | KDM4E (0.50) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL16395691 | 0.76 | POLB (0.50) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL17763436 | 0.76 | POLB (0.50) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL6542407 | 0.76 | GABRA1 (0.43) | HPGDALOX15 | |
| SCHEMBL3194641 | 0.76 | KDM4E (0.48) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL22552676 | 0.74 | KDM4E (0.52) | KDM4EGLAMYCNR4A1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11148991-B2 | 5-bromo-2-(alpha-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2021-10-19 | — | — | US | disclosed |
| US-10604471-B2 | 5-bromo-2-(alpha-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2020-03-31 | — | — | US | disclosed |
| US-20190315673-A1 | 5-BROMO-2-(alpha-HYDROXYPENTYL)BENZOIC ACID SODIUM SALTS IN DIFFERENT CRYSTAL FORMS, AND PREPARATION METHOD THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
| US-10377693-B2 | 5-bromo-2-(α-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2019-08-13 | — | — | US | disclosed |
| US-20190194116-A1 | 5-BROMO-2-(alpha-HYDROXYPENTYL)BENZOIC ACID SODIUM SALTS IN DIFFERENT CRYSTAL FORMS, AND PREPARATION METHOD THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2019-06-27 | — | — | US | disclosed |
| US-20180127349-A1 | 5-BROMO-2-(alpha-HYDROXYPENTYL)BENZOIC ACID SODIUM SALTS IN DIFFERENT CRYSTAL FORMS, AND PREPARATION METHOD THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2018-05-10 | — | — | US | disclosed |
| US-9902682-B2 | 5-bromo-2-(alpha-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) | 2018-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10377693-B2 | 5-bromo-2-(α-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | GABRA5, NPY5R, SCN5A | KDM4E 953/4885GLA 622/4885MYC 4336/4885 |
| US-20190315673-A1 | 5-BROMO-2-(alpha-HYDROXYPENTYL)BENZOIC ACID SODIUM SALTS IN DIFFERENT CRYSTAL FORMS, AND PREPARATION METHOD THEREOF | GABRA5, NPY5R, SLC9A5 | KDM4E 921/4885GLA 658/4885MYC 4408/4885 |
| US-11148991-B2 | 5-bromo-2-(alpha-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | GABRA5, NPY5R, SLC9A5 | KDM4E 921/4885GLA 658/4885MYC 4408/4885 |
| US-10604471-B2 | 5-bromo-2-(alpha-hydroxypentyl)benzoic acid sodium salts in different crystal forms, and preparation method thereof | GABRA5, NPY5R, SLC9A5 | KDM4E 921/4885GLA 658/4885MYC 4408/4885 |
| US-20180127349-A1 | 5-BROMO-2-(alpha-HYDROXYPENTYL)BENZOIC ACID SODIUM SALTS IN DIFFERENT CRYSTAL FORMS, AND PREPARATION METHOD THEREOF | GABRA5, NPY5R, SLC9A5 | KDM4E 921/4885GLA 658/4885MYC 4408/4885 |
| US-20190194116-A1 | 5-BROMO-2-(alpha-HYDROXYPENTYL)BENZOIC ACID SODIUM SALTS IN DIFFERENT CRYSTAL FORMS, AND PREPARATION METHOD THEREOF | GABRA5, NPY5R, SLC9A5 | KDM4E 921/4885GLA 658/4885MYC 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.