Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11613901 | 0.84 | KDM4E (0.50) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL24680076 | 0.82 | KDM4E (0.53) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL19901920 | 0.81 | KDM4E (0.52) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL30058887 | 0.78 | NR4A2 (0.53) | CYP1A2CYP2C9HPGDCYP2C19MAPT | |
| SCHEMBL4084280 | 0.78 | NR4A2 (0.53) | CYP1A2CYP2C9HPGDCYP2C19MAPT | |
| SCHEMBL618056 | 0.76 | KDM4E (0.65) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL3172075 | 0.75 | KDM4E (0.50) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL29571243 | 0.75 | KDM4E (0.59) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL17332 | 0.75 | KDM4E (0.59) | KDM4EGLAMYCNR4A1SORT1 | |
| SCHEMBL2482965 | 0.74 | KDM4E (0.63) | KDM4EGLAMYCNR4A1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105779-A | Preparation method of 5-bromo-2-formylbenzoic acid methyl ester | 河南师范大学 | 2023-11-24 | — | — | CN | disclosed |
| EP-1848463-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES | Amgen Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | AMGEN INC. | 2006-09-07 | — | — | US | disclosed |
| WO-2006079099-A2 | METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO A POLYMER | AMGEN INC. (US) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199812-A1 | Method of conjugating aminothiol containing molecules to vehicles | SLC7A1, QPCT, SLC7A5 | KDM4E 4444/4885GLA 4023/4885MYC 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.