Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383072 | 0.81 | HIF1A (0.53) | ESR1ESR2SLC22A1OPRM1HIF1A | |
| SCHEMBL6395780 | 0.80 | ESR1 (0.38) | ESR1ESR2SLC22A1OPRM1HIF1A | |
| SCHEMBL19902003 | 0.78 | TYR (0.40) | ESR1ESR2TSHRGABRA1GABRB2 | |
| SCHEMBL6402386 | 0.77 | ESR1 (0.38) | ESR1ESR2SLC22A1OPRM1HIF1A | |
| SCHEMBL6395778 | 0.77 | ESR1 (0.35) | ESR1ESR2SLC22A1OPRM1HIF1A | |
| SCHEMBL6396108 | 0.77 | POLB (0.36) | ESR1ESR2SLC22A1OPRM1HIF1A | |
| SCHEMBL29492448 | 0.76 | ALOX5 (0.49) | ESR1ESR2LMNATSHRGAA | |
| SCHEMBL21830520 | 0.76 | ALOX5 (0.49) | ESR1ESR2LMNATSHRGAA | |
| SCHEMBL21164589 | 0.75 | SLC22A1 (0.47) | ESR1ESR2SLC22A1OPRM1HIF1A | |
| SCHEMBL6397679 | 0.74 | ESR1 (0.38) | ESR1ESR2SLC22A1OPRM1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902798-B2 | Compound containing phenolic hydroxyl group, phenolic resin, curable composition, cured product thereof, semiconductor sealing material, and printed circuit board | DIC CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |