Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11193682 | 0.89 | TYR (0.49) | ESR1ESR2GABRA1GABRB2EGFR | |
| SCHEMBL1899586 | 0.88 | ESR1 (0.68) | ESR1ESR2GABRA1GABRB2PDCD1 | |
| SCHEMBL7058427 | 0.86 | ESR1 (0.51) | ESR1ESR2GABRA1GABRB2PDCD1 | |
| SCHEMBL5159407 | 0.85 | ESR1 (0.58) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL10706145 | 0.81 | ESR1 (0.58) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL5877825 | 0.80 | GABRA1 (0.68) | ESR1GABRA1GABRB2EGFRTYR | |
| SCHEMBL4289027 | 0.80 | TYR (0.46) | GABRA1GABRB2EGFRTYR | |
| SCHEMBL28231502 | 0.80 | ESR1 (0.56) | ESR1ESR2GABRA1GABRB2PDCD1 | |
| SCHEMBL3235535 | 0.79 | ESR1 (0.55) | ESR1ESR2PDCD1CD274MIF | |
| SCHEMBL2472270 | 0.79 | ESR1 (0.64) | ESR1ESR2GABRA1GABRB2PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902798-B2 | Compound containing phenolic hydroxyl group, phenolic resin, curable composition, cured product thereof, semiconductor sealing material, and printed circuit board | DIC CORPORATION (JP) | 2018-02-27 | — | — | US | disclosed |