Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.35 |
| ▸ | STK24 | Q9Y6E0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16489247 | 0.80 | NPC1 (0.44) | MAPTSMN1; SMN2PKMKAT6ANPC1 | |
| SCHEMBL19902804 | 0.71 | BLM (0.39) | MAPTALDH1A1LMNA | |
| SCHEMBL10622670 | 0.68 | EGLN2 (0.41) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5763437 | 0.67 | CLCN2 (0.41) | MAPTSMN1; SMN2KAT6AKMT2ANPC1 | |
| SCHEMBL11452798 | 0.66 | NPC1 (0.48) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL19902737 | 0.66 | RAB9A (0.54) | MAPTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6961935 | 0.66 | GAA (0.46) | MAPTKAT6AKMT2AALDH1A1HTT | |
| SCHEMBL16489244 | 0.65 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL25121244 | 0.65 | TTR (0.35) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18398312 | 0.65 | TTR (0.44) | MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3033337-B1 | SUBSTITUTED IMIDAZOLES AS N-TYPE CALCIUM CHANNEL BLOCKERS | JANSSEN PHARMACEUTICA NV (BE) | 2018-02-28 | — | — | EP | disclosed |