Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 13/20 | 0.38 |
| ▸ | SORD | Q00796 | 2/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22383489 | 0.67 | GBA1 (0.42) | MAPK1NPSR1GBA1SORDALDH1A1 | |
| SCHEMBL22383535 | 0.67 | HCRTR1 (0.44) | GBA1SORD | |
| SCHEMBL14872339 | 0.67 | CRHBP (0.59) | MEN1KMT2AMAPK1HTTSMN1; SMN2 | |
| SCHEMBL19903095 | 0.65 | GBA1 (0.35) | NPSR1GBA1SORD | |
| SCHEMBL19903104 | 0.64 | PHGDH (0.38) | HTTSMN1; SMN2GBA1SORDPHGDH | |
| SCHEMBL5790244 | 0.64 | SMN1; SMN2 (0.65) | MEN1KMT2AMAPK1HTTSMN1; SMN2 | |
| SCHEMBL5791348 | 0.63 | SMN1; SMN2 (0.68) | MEN1KMT2AMAPK1HTTSMN1; SMN2 | |
| SCHEMBL22383442 | 0.60 | HCRTR1 (0.70) | GBA1 | |
| SCHEMBL19903117 | 0.59 | USP2 (0.42) | MEN1KMT2ASMN1; SMN2GBA1ALDH1A1 | |
| SCHEMBL22275729 | 0.59 | HRH4 (0.59) | KMT2ASMN1; SMN2NPSR1SORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287454-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |