Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.44 |
| ▸ | SORD | Q00796 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 10/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22383442 | 0.76 | HCRTR1 (0.70) | HCRTR1HCRTR2GBA1 | |
| SCHEMBL20212722 | 0.75 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL19893906 | 0.73 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL22383489 | 0.69 | GBA1 (0.42) | HCRTR1HCRTR2SORDGBA1 | |
| SCHEMBL19903143 | 0.67 | MEN1 (0.41) | SORDGBA1 | |
| SCHEMBL14872339 | 0.67 | CRHBP (0.59) | SORDGBA1 | |
| SCHEMBL16847391 | 0.64 | HCRTR1 (0.69) | HCRTR1HCRTR2GBA1 | |
| SCHEMBL5790244 | 0.64 | SMN1; SMN2 (0.65) | SORDGBA1 | |
| SCHEMBL5791348 | 0.63 | SMN1; SMN2 (0.68) | SORDGBA1 | |
| SCHEMBL19893859 | 0.62 | ALDH1A1 (0.42) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287454-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |