SCHEMBL19903518

SCHEMBL19903518

N#Cc1c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1-n1c2ccccc2c2cc(-c3ccccc3)ccc21

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ICMT O60725 4/20 0.37
RXRA P19793 3/20 0.37
RXRG P48443 3/20 0.37
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TACR1 P25103 3/20 0.35
KIF11 P52732 3/20 0.35
RXRB P28702 2/20 0.35
TSPO P30536 1/20 0.34
NAAA Q02083 1/20 0.33
GLO1 Q04760 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19903550 0.96 ICMT (0.37) ICMTRXRARXRGALDH1A1MAPT
SCHEMBL19903526 0.96 RXRA (0.39) ICMTRXRARXRGALDH1A1MAPT
SCHEMBL22564447 0.95 RXRA (0.45) ICMTRXRARXRGALDH1A1MAPT
SCHEMBL19903596 0.94 KDM4E (0.40) ICMTRXRARXRGALDH1A1MAPT
SCHEMBL19903456 0.93 KIF11 (0.42) ICMTRXRARXRGTACR1KIF11
SCHEMBL19917999 0.93 RXRA (0.37) ICMTRXRARXRGALDH1A1MAPT
SCHEMBL19912379 0.93 AR (0.35) ICMTRXRARXRGALDH1A1MAPT
SCHEMBL19917798 0.92 AR (0.38) ICMTRXRARXRGALDH1A1MAPT
SCHEMBL20617440 0.92 RXRA (0.41) ICMTRXRARXRGALDH1A1MAPT
SCHEMBL21108761 0.92 ICMT (0.34) ICMTRXRARXRGALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-10-08 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
EP-3287450-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-03-20 EP disclosed
US-9917270-B1 Organic electroluminescent device having an exciton quenching layer CYNORA GMBH (DE) 2018-03-13 US disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287450-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, ORC3, AOC3 ICMT 156/4885RXRA 3779/4885RXRG 3669/4885
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 ICMT 127/4885RXRA 3635/4885RXRG 3474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.