SCHEMBL19903530

SCHEMBL19903530

Cc1ccc2c(c1)c1ccccc1n2-c1cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(-n2c3ccccc3c3cc(C)ccc32)cc1C#N

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 5/20 0.34
KIF11 P52732 1/20 0.34
HRH1 P35367 1/20 0.32
HTR6 P50406 1/20 0.32
RORC P51449 1/20 0.32
KDM4E B2RXH2 3/20 0.32
HTT P42858 2/20 0.32
ALDH1A1 P00352 2/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
NCOA1 Q15788 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HIF1A Q16665 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
TACR1 P25103 2/20 0.32
IMPDH2 P12268 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19912413 0.96 AR (0.35) ARKIF11HRH1HTR6RORC
SCHEMBL19903604 0.96 AR (0.36) ARKIF11HRH1HTR6KDM4E
SCHEMBL22564470 0.95 RXRA (0.34) ARKIF11HRH1HTR6RORC
SCHEMBL19903576 0.94 AR (0.34) ARKIF11HRH1HTR6RORC
SCHEMBL19903509 0.94 KIF11 (0.36) ARKIF11KDM4EHTTALDH1A1
SCHEMBL19912422 0.93 KIF11 (0.36) ARKIF11HRH1HTR6RORC
SCHEMBL19912387 0.91 AR (0.35) ARKIF11HRH1HTR6HTT
SCHEMBL19917988 0.91 AR (0.38) ARKIF11KDM4EHTTALDH1A1
SCHEMBL19903500 0.91 KIF11 (0.37) ARKIF11KDM4ECTSSCTSK
SCHEMBL19917912 0.91 AR (0.40) ARKDM4ENCOA1NCOA3TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-10-08 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287450-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, ORC3, AOC3 AR 4190/4885KIF11 3253/4885HRH1 3242/4885
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 AR 4212/4885KIF11 3316/4885HRH1 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.