SCHEMBL19903574

SCHEMBL19903574

Cc1cccc2c3ccccc3n(-c3cc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)cc(-n4c5ccccc5c5cccc(C)c54)c3C#N)c12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALKBH5 Q6P6C2 1/20 0.39
FTO Q9C0B1 1/20 0.39
KIF11 P52732 1/20 0.36
BCAT1 P54687 2/20 0.36
BCAT2 O15382 1/20 0.36
POLB P06746 1/20 0.33
AR P10275 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
LMNA P02545 2/20 0.32
HTT P42858 1/20 0.32
RXRA P19793 2/20 0.32
ALDH1A1 P00352 2/20 0.32
RXRB P28702 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19912333 0.95 ALKBH5 (0.36) ALKBH5FTOKIF11BCAT1BCAT2
SCHEMBL19903495 0.88 KIF11 (0.39) KIF11RXRAALDH1A1RXRBKDM4E
SCHEMBL19912331 0.88 BCAT1 (0.35) KIF11BCAT1BCAT2POLBAR
SCHEMBL19912336 0.87 POLB (0.35) BCAT1BCAT2POLBARCYP1A2
SCHEMBL26776532 0.85 KIF11 (0.37) ALKBH5FTOKIF11BCAT1BCAT2
SCHEMBL19912373 0.85 KIF11 (0.38) KIF11BCAT1BCAT2POLBAR
SCHEMBL19903684 0.84 KDM4E (0.41) KIF11ARLMNARXRAALDH1A1
SCHEMBL19917906 0.84 KIF11 (0.39) KIF11BCAT1BCAT2POLBAR
SCHEMBL19903464 0.84 KIF11 (0.36) KIF11BCAT1BCAT2POLBAR
SCHEMBL19903570 0.84 AR (0.44) KIF11BCAT1BCAT2ARRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-10-08 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
EP-3287450-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-03-20 EP disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287450-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, ORC3, AOC3 ALKBH5 2983/4885FTO 352/4885KIF11 3253/4885
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 ALKBH5 2859/4885FTO 336/4885KIF11 3316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.