Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15783775 | 0.74 | CHRM3 (0.60) | CHRM3SMN1; SMN2KMT2ASPHK2SPHK1 | |
| SCHEMBL19984510 | 0.73 | CHRM3 (0.64) | CHRM3SMN1; SMN2KMT2ASPHK2SPHK1 | |
| SCHEMBL19903889 | 0.73 | CHRM3 (0.43) | CHRM3KMT2AADRB2RXRARXRB | |
| SCHEMBL19984492 | 0.73 | CHRM3 (0.42) | CHRM3SMN1; SMN2KMT2ABCHE | |
| SCHEMBL14241401 | 0.72 | CHRM3 (0.46) | CHRM3SMN1; SMN2KMT2ASPHK2SPHK1 | |
| SCHEMBL28850003 | 0.72 | TDP1 (0.59) | SMN1; SMN2KMT2AADRB2ADRB1ADRB3 | |
| SCHEMBL20373866 | 0.71 | CHRM3 (0.62) | CHRM3SMN1; SMN2KMT2ASPHK2SPHK1 | |
| SCHEMBL19984677 | 0.71 | RXRA (0.57) | CHRM3SMN1; SMN2KMT2ASPHK2SPHK1 | |
| SCHEMBL19984429 | 0.71 | CHRM3 (0.62) | CHRM3SMN1; SMN2KMT2ASPHK2SPHK1 | |
| SCHEMBL3443226 | 0.71 | KMT2A (0.53) | SMN1; SMN2KMT2AADRB2ADRB3NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |