Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 7/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984510 | 0.77 | CHRM3 (0.64) | CHRM3MAOBMEN1KMT2ANPC1 | |
| SCHEMBL19984429 | 0.76 | CHRM3 (0.62) | CHRM3NR4A2RXRARXRBRXRG | |
| SCHEMBL20373866 | 0.76 | CHRM3 (0.62) | CHRM3NR4A2RXRARXRBRXRG | |
| SCHEMBL19903884 | 0.74 | MAOA (0.53) | CHRM3NR4A2MAOAMAOBKMT2A | |
| SCHEMBL19903833 | 0.73 | CHRM3 (0.45) | CHRM3NR4A2RXRARXRBRXRG | |
| SCHEMBL15777842 | 0.72 | SMPD1 (0.55) | CHRM3NR4A2RXRARXRBMAOA | |
| SCHEMBL15777839 | 0.72 | SMPD1 (0.55) | CHRM3NR4A2RXRARXRBMAOA | |
| SCHEMBL15783775 | 0.70 | CHRM3 (0.60) | CHRM3NR4A2RXRARXRBRXRG | |
| SCHEMBL16715064 | 0.70 | CHRM3 (0.46) | CHRM3MEN1KMT2AADRB2PTGES | |
| SCHEMBL16715065 | 0.70 | CHRM3 (0.46) | CHRM3MEN1KMT2AADRB2PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |