Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 17/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 14/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984448 | 0.84 | CHRM3 (0.44) | CHRM3ADRB2CACNA1C | |
| SCHEMBL20373767 | 0.81 | CHRM3 (0.40) | CHRM3ADRB2 | |
| SCHEMBL19903850 | 0.79 | CHRM3 (0.39) | CHRM3ADRB2CACNA1C | |
| SCHEMBL19984720 | 0.78 | CHRM3 (0.40) | CHRM3ADRB2 | |
| SCHEMBL19903829 | 0.78 | ADRB2 (0.44) | CHRM3ADRB2 | |
| SCHEMBL19903848 | 0.76 | CHRM3 (0.42) | CHRM3ADRB2CACNA1C | |
| SCHEMBL19903847 | 0.75 | ADRB2 (0.57) | CHRM3ADRB2CACNA1C | |
| SCHEMBL19984610 | 0.74 | ADRB2 (0.43) | CHRM3ADRB2 | |
| SCHEMBL19984506 | 0.74 | ADRB2 (0.43) | CHRM3ADRB2 | |
| SCHEMBL19903823 | 0.73 | ADRB2 (0.44) | CHRM3ADRB2CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |