Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 12/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984448 | 0.86 | CHRM3 (0.44) | CHRM3ADRB2 | |
| SCHEMBL19984720 | 0.86 | CHRM3 (0.40) | CHRM3ADRB2BCHE | |
| SCHEMBL19984506 | 0.82 | ADRB2 (0.43) | CHRM3ADRB2 | |
| SCHEMBL19903823 | 0.82 | ADRB2 (0.44) | CHRM3ADRB2 | |
| SCHEMBL19903854 | 0.81 | CHRM3 (0.40) | CHRM3ADRB2 | |
| SCHEMBL19984610 | 0.80 | ADRB2 (0.43) | CHRM3ADRB2 | |
| SCHEMBL20373307 | 0.77 | ADRB2 (0.59) | CHRM3ADRB2 | |
| SCHEMBL19903829 | 0.77 | ADRB2 (0.44) | CHRM3ADRB2 | |
| SCHEMBL20373390 | 0.74 | ADRB2 (0.56) | CHRM3ADRB2 | |
| SCHEMBL19984714 | 0.72 | ADRB2 (0.55) | CHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.a. (IT) | 2018-07-11 | — | — | EP | disclosed |