Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 15/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984610 | 0.89 | ADRB2 (0.43) | ADRB2CHRM3 | |
| SCHEMBL19984720 | 0.88 | CHRM3 (0.40) | ADRB2CHRM3 | |
| SCHEMBL19984448 | 0.85 | CHRM3 (0.44) | ADRB2CHRM3 | |
| SCHEMBL20373848 | 0.82 | ADRB2 (0.60) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL20373767 | 0.82 | CHRM3 (0.40) | ADRB2CHRM3 | |
| SCHEMBL19903823 | 0.75 | ADRB2 (0.44) | ADRB2CHRM3 | |
| SCHEMBL19903829 | 0.75 | ADRB2 (0.44) | ADRB2CHRM3 | |
| SCHEMBL19903854 | 0.74 | CHRM3 (0.40) | ADRB2CHRM3 | |
| SCHEMBL15772481 | 0.73 | CHRM3 (0.80) | ADRB2CHRM3 | |
| SCHEMBL15772477 | 0.73 | CHRM3 (0.80) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928889-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-03-21 | — | — | EP | disclosed |