Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904003 | 0.85 | PHLPP2 (0.33) | TSHRPHLPP2CYP2D6MAOAHTR3A | |
| SCHEMBL14679866 | 0.82 | THRB (0.43) | TSHRPHLPP2CYP2D6MAOAHTR3A | |
| SCHEMBL19904030 | 0.78 | TSHR (0.49) | TSHRPHLPP2CYP2D6MAOAHTR3A | |
| SCHEMBL19981010 | 0.76 | THRB (0.38) | TSHRPHLPP2CYP2D6MAOAHTR3A | |
| SCHEMBL19980951 | 0.76 | MAPT (0.38) | TSHRPHLPP2CYP2D6MAOAHTR3A | |
| SCHEMBL15682924 | 0.73 | TSHR (0.55) | TSHRTHRBHPGD | |
| SCHEMBL21322323 | 0.72 | PHLPP2 (0.47) | TSHRPHLPP2CYP2D6MAOAHTR3A | |
| SCHEMBL14341772 | 0.72 | THRB (0.43) | TSHRNPSR1THRBHPGD | |
| SCHEMBL13206328 | 0.72 | ESRRG (0.42) | TSHRPHLPP2CYP2D6MAOAHTR3A | |
| SCHEMBL17067685 | 0.72 | TSHR (0.58) | TSHRTHRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233944-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-09-04 | — | — | EP | disclosed |
| EP-2393849-B1 | COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2019-06-19 | — | — | EP | disclosed |
| EP-2393851-B1 | COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-02-28 | — | — | EP | disclosed |