Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 14/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904659 | 1.00 | CHRM4 (0.47) | CHRM4CHRM2CHRM1UGCGALK | |
| SCHEMBL19904331 | 0.91 | NOTUM (0.42) | CHRM4CHRM2UGCG | |
| SCHEMBL19904682 | 0.90 | UGCG (0.48) | UGCG | |
| SCHEMBL19904428 | 0.90 | UGCG (0.43) | UGCG | |
| SCHEMBL19904316 | 0.90 | UGCG (0.43) | UGCG | |
| SCHEMBL19904478 | 0.89 | UGCG (0.43) | UGCG | |
| SCHEMBL19904704 | 0.88 | P2RX3 (0.40) | UGCG | |
| SCHEMBL19904565 | 0.88 | HTR1A (0.44) | CHRM4UGCG | |
| SCHEMBL19904680 | 0.88 | UGCG (0.42) | UGCG | |
| SCHEMBL19904575 | 0.88 | ACACB (0.40) | UGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063141-B1 | N-(1-HYDROXY-3-(PYRROLIDINYL)PROPAN-2-YL)PYRROLIDINE-3-CARBOXAMIDE DERIVATIVES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | BIOMARIN PHARM INC (US) | 2018-02-28 | — | — | EP | disclosed |