Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904747 | 0.81 | MAOB (0.39) | MAOBLTA4HCYP1A2CYP2C19TSHR | |
| SCHEMBL255565 | 0.80 | TSHR (0.54) | MAOBLTA4HCYP1A2CYP19A1CYP2C9 | |
| SCHEMBL30167692 | 0.80 | TSHR (0.54) | MAOBLTA4HCYP1A2CYP19A1CYP2C9 | |
| SCHEMBL445915 | 0.80 | LTA4H (0.53) | LTA4HCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL19904760 | 0.78 | CETP (0.44) | LTA4HCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11227351 | 0.77 | NFE2L2 (0.41) | MAOBNFE2L2 | |
| SCHEMBL430999 | 0.76 | LTA4H (0.53) | LTA4HCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL29033057 | 0.75 | LTA4H (0.52) | LTA4HCYP1A2CYP2C9CYP2C19TSHR | |
| SCHEMBL991869 | 0.75 | LTA4H (0.53) | LTA4HTSHRTP53 | |
| SCHEMBL10477053 | 0.75 | TSHR (0.62) | LTA4HCYP1A2CYP19A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020507-A2 | ORGANOPHOSPHOROUS COMPOUNDS AND USES THEREOF | JAL THERAPEUTICS, LLC (US) | 2024-01-25 | — | — | WO | disclosed |
| EP-2097428-B1 | BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MGP BIOTECHNOLOGIES INC (US) | 2018-02-28 | — | — | EP | disclosed |