Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904703 | 0.82 | MGLL (0.40) | ALDH1A1MAPTKDM4ELMNALTA4H | |
| SCHEMBL19904727 | 0.81 | MAOB (0.40) | MAOBLTA4HCYP1A2CYP2C19TSHR | |
| SCHEMBL4194351 | 0.80 | ALDH1A1 (0.55) | MAOBALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL445915 | 0.80 | LTA4H (0.53) | ALDH1A1LMNALTA4HCYP1A2CYP2D6 | |
| SCHEMBL19904760 | 0.78 | CETP (0.44) | MAPTKDM4ELTA4HCYP1A2CYP2C19 | |
| SCHEMBL6244032 | 0.77 | MAOB (0.48) | MAOBALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL430999 | 0.76 | LTA4H (0.53) | ALDH1A1LMNALTA4HCYP1A2CYP2D6 | |
| SCHEMBL29033057 | 0.75 | LTA4H (0.52) | ALDH1A1LMNALTA4HCYP1A2CYP2C19 | |
| SCHEMBL2570157 | 0.75 | TSHR (0.62) | MAOBALDH1A1MAPTKMT2AKDM4E | |
| SCHEMBL991869 | 0.75 | LTA4H (0.53) | ALDH1A1LMNALTA4HTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097428-B1 | BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MGP BIOTECHNOLOGIES INC (US) | 2018-02-28 | — | — | EP | disclosed |