Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904757 | 0.93 | GAA (0.43) | GAAMAPK1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3228871 | 0.84 | GAA (0.56) | GAAMAPK1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3230831 | 0.82 | GAA (0.56) | GAAMAPK1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL30722914 | 0.82 | GAA (0.56) | GAAMAPK1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL19904746 | 0.76 | L3MBTL1 (0.50) | GAAMAPK1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL4431205 | 0.73 | CYP3A4 (0.50) | GAAMAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL3234851 | 0.72 | CYP3A4 (0.53) | L3MBTL1MEN1KMT2A | |
| SCHEMBL17355861 | 0.72 | CYP3A4 (0.46) | GAAMEN1KMT2A | |
| SCHEMBL27042296 | 0.72 | KMT2A (0.50) | KMT2A | |
| SCHEMBL19904719 | 0.71 | GLA (0.41) | TDP1L3MBTL1SMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097428-B1 | BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MGP BIOTECHNOLOGIES INC (US) | 2018-02-28 | — | — | EP | disclosed |