Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904746 | 0.80 | L3MBTL1 (0.50) | GLASMN1; SMN2L3MBTL1TDP1PKM | |
| SCHEMBL3226269 | 0.78 | CYP3A4 (0.48) | L3MBTL1FAAHXBP1HTTNPSR1 | |
| SCHEMBL19904757 | 0.76 | GAA (0.43) | GLASMN1; SMN2L3MBTL1TDP1S1PR1 | |
| SCHEMBL3230857 | 0.73 | TDP1 (0.48) | SMN1; SMN2L3MBTL1TDP1PKM | |
| SCHEMBL3222691 | 0.73 | PKM (0.51) | SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL30722828 | 0.73 | PKM (0.51) | SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL3224957 | 0.72 | L3MBTL1 (0.52) | SMN1; SMN2L3MBTL1PKM | |
| SCHEMBL19904728 | 0.71 | GAA (0.48) | GLASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL19904708 | 0.71 | PKM (0.41) | GLASMN1; SMN2L3MBTL1TDP1PKM | |
| SCHEMBL19904763 | 0.71 | PKM (0.49) | SMN1; SMN2L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097428-B1 | BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MGP BIOTECHNOLOGIES INC (US) | 2018-02-28 | — | — | EP | disclosed |