Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30722914 | 0.85 | GAA (0.56) | L3MBTL1GAAMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL3230831 | 0.85 | GAA (0.56) | L3MBTL1GAAMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL3228871 | 0.83 | GAA (0.56) | L3MBTL1GAAMAPK1SMN1; SMN2TDP1 | |
| SCHEMBL3238027 | 0.82 | PKM (0.51) | L3MBTL1PKMSMN1; SMN2LMNA | |
| SCHEMBL19904719 | 0.80 | GLA (0.41) | L3MBTL1PKMSMN1; SMN2GLATDP1 | |
| SCHEMBL20067126 | 0.80 | L3MBTL1 (0.51) | L3MBTL1PKMSMN1; SMN2LMNA | |
| SCHEMBL30722828 | 0.80 | PKM (0.51) | L3MBTL1PKMSMN1; SMN2LMNA | |
| SCHEMBL3222691 | 0.80 | PKM (0.51) | L3MBTL1PKMSMN1; SMN2LMNA | |
| SCHEMBL3224957 | 0.79 | L3MBTL1 (0.52) | L3MBTL1PKMSMN1; SMN2LMNA | |
| SCHEMBL19904757 | 0.79 | GAA (0.43) | L3MBTL1GAAMAPK1SMN1; SMN2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097428-B1 | BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MGP BIOTECHNOLOGIES INC (US) | 2018-02-28 | — | — | EP | disclosed |