Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.32 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | BLK | P51451 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906192 | 0.94 | PTGDR2 (0.32) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906147 | 0.90 | PTGDR2 (0.36) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19905855 | 0.88 | KDM4E (0.39) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906280 | 0.87 | KDM4E (0.34) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906171 | 0.87 | KDM4E (0.36) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906167 | 0.86 | PTGES2 (0.36) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906405 | 0.85 | KDM4E (0.35) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906197 | 0.84 | PTGDR2 (0.36) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906078 | 0.83 | SHMT1 (0.31) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906361 | 0.83 | KDM4E (0.33) | KDM4EPTGDR2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |