Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.31 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906280 | 0.91 | KDM4E (0.34) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906192 | 0.90 | PTGDR2 (0.32) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906080 | 0.90 | CNR1 (0.35) | PTGDR2KDM4ECNR1MEN1ALDH1A1 | |
| SCHEMBL19906283 | 0.86 | KDM4E (0.33) | PTGDR2EIF4EBP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL19906145 | 0.85 | KEAP1 (0.34) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906167 | 0.84 | PTGES2 (0.36) | PTGDR2EIF4EBP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL19905856 | 0.83 | KDM4E (0.35) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906369 | 0.83 | KDM4E (0.38) | PTGDR2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906102 | 0.83 | KDM4E (0.32) | PTGDR2EIF4EBP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL19906193 | 0.83 | CASP3 (0.33) | PTGDR2KDM4EPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |