Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHMT1 | P34896 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.34 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.33 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906059 | 0.92 | KDM4E (0.33) | SHMT1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906036 | 0.89 | PTGDR2 (0.40) | SHMT1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906369 | 0.89 | KDM4E (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906328 | 0.88 | PTGER1 (0.34) | SHMT1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19905802 | 0.87 | MAP4K4 (0.43) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906229 | 0.86 | EIF4E (0.36) | SHMT1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906268 | 0.85 | EIF4E (0.38) | SHMT1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906322 | 0.85 | CNR1 (0.38) | SHMT1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906291 | 0.85 | PTGDR2 (0.33) | SHMT1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL19906239 | 0.85 | PTGDR2 (0.35) | SHMT1KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |