Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 2/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.31 |
| ▸ | ROS1 | P08922 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906328 | 0.94 | PTGER1 (0.34) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906044 | 0.92 | SHMT1 (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19905772 | 0.88 | MAP4K4 (0.41) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906369 | 0.87 | KDM4E (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906229 | 0.86 | EIF4E (0.36) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906366 | 0.85 | CTSA (0.34) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906268 | 0.85 | EIF4E (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906288 | 0.84 | CSF1R (0.35) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906122 | 0.84 | KDM4C (0.34) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906211 | 0.84 | KDM4E (0.34) | KDM4EMEN1ALDH1A1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |