Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | EIF4E | P06730 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906046 | 0.87 | EIF4E (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906139 | 0.84 | PTGDR2 (0.43) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906092 | 0.83 | PTGDR2 (0.48) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906105 | 0.81 | PTGDR2 (0.42) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906247 | 0.81 | ABL1 (0.40) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906088 | 0.80 | KDM4E (0.42) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15342570 | 0.80 | CYP3A4 (0.40) | KDM4EEIF4ERAB9AHSD11B1NPC1 | |
| SCHEMBL19906210 | 0.79 | PTGDR2 (0.42) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906240 | 0.79 | PTGDR2 (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906327 | 0.79 | PTGDR2 (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |