Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 8/20 | 0.37 |
| ▸ | ITK | Q08881 | 8/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906014 | 0.87 | PTGDR2 (0.39) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906329 | 0.84 | KDM4E (0.36) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19905852 | 0.84 | KDM4E (0.35) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906265 | 0.84 | KDM4E (0.35) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906236 | 0.83 | PTGDR2 (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19905772 | 0.83 | MAP4K4 (0.41) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL15333389 | 0.83 | CYP3A4 (0.36) | ABL1BTKITKCCNT1CCNA2 | |
| SCHEMBL15333762 | 0.83 | CYP3A4 (0.36) | ABL1BTKITKCCNT1CCNA2 | |
| SCHEMBL19906269 | 0.83 | EIF4E (0.40) | KDM4EMEN1ALDH1A1KMT2APTGDR2 | |
| SCHEMBL19906015 | 0.82 | PIK3CG (0.38) | KDM4EMEN1ALDH1A1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |