Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906049 | 0.87 | PTGDR2 (0.40) | EIF4EPTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906137 | 0.87 | PTGDR2 (0.39) | EIF4EPTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906104 | 0.83 | KDM4E (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906086 | 0.82 | KDM4E (0.39) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906239 | 0.82 | PTGDR2 (0.35) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906197 | 0.82 | PTGDR2 (0.36) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905892 | 0.82 | PTGDR2 (0.37) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906119 | 0.82 | PTGDR2 (0.39) | EIF4EPTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906229 | 0.81 | EIF4E (0.36) | EIF4EPTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906369 | 0.81 | KDM4E (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |