Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906236 | 0.93 | PTGDR2 (0.38) | EIF4EPTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906268 | 0.88 | EIF4E (0.38) | EIF4EPTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19905874 | 0.85 | PTGDR2 (0.35) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906015 | 0.85 | PIK3CG (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906249 | 0.84 | ALDH1A1 (0.43) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19906329 | 0.84 | KDM4E (0.36) | EIF4EPTGDR2KDM4EALDH1A1MEN1 | |
| SCHEMBL19906287 | 0.84 | KDR (0.37) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL19905858 | 0.83 | USP2 (0.38) | PTGDR2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15342614 | 0.83 | CYP3A4 (0.38) | EIF4EALDH1A1MAPTTRPM8LMNA | |
| SCHEMBL19905939 | 0.83 | PTGDR2 (0.35) | PTGDR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |