Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906018 | 0.91 | KDM4E (0.35) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19905880 | 0.90 | KDM4E (0.38) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19905850 | 0.88 | KDM4E (0.36) | KDM4EPIK3CDPIK3CAPI4KAPIK3CG | |
| SCHEMBL19905831 | 0.87 | PIK3CD (0.42) | KDM4EPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL19906086 | 0.85 | KDM4E (0.39) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906060 | 0.83 | KDM4E (0.38) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906314 | 0.83 | KDM4E (0.40) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906157 | 0.83 | KDM4E (0.38) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19905988 | 0.82 | KDM4E (0.35) | KDM4EPTGDR2MEN1ALDH1A1KMT2A | |
| SCHEMBL19906322 | 0.81 | CNR1 (0.38) | KDM4EPTGDR2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |