Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 5/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906060 | 0.92 | KDM4E (0.38) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19906157 | 0.92 | KDM4E (0.38) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19905880 | 0.87 | KDM4E (0.38) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19906322 | 0.87 | CNR1 (0.38) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19905988 | 0.87 | KDM4E (0.35) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19906088 | 0.86 | KDM4E (0.42) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19906137 | 0.86 | PTGDR2 (0.39) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19905850 | 0.85 | KDM4E (0.36) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19906061 | 0.85 | KDM4E (0.37) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL19906314 | 0.85 | KDM4E (0.40) | KDM4EPTGDR2KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |