Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906075 | 0.90 | MAPT (0.36) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL19906249 | 0.89 | ALDH1A1 (0.43) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL15342551 | 0.82 | CYP3A4 (0.38) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL19906015 | 0.81 | PIK3CG (0.38) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL15342143 | 0.80 | LMNA (0.33) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL19906139 | 0.79 | PTGDR2 (0.43) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL19906236 | 0.79 | PTGDR2 (0.38) | ALDH1A1KDM4EHPGDPTGDR2KMT2A | |
| SCHEMBL19906081 | 0.79 | MAPT (0.37) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL19906369 | 0.79 | KDM4E (0.38) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL19906090 | 0.77 | MEN1 (0.39) | ALDH1A1KDM4EHPGDPTGDR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |